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MRSA Treatment Guidelines

MRSA treatment will usually involve up to 4 different types of actions that can be taken. Your doctors can help you get rid of this infection.

Personal care & MRSA treatment

One of the first steps in your MRSA treatment will be using a soap like Hibiclens which can  help remove the bacteria from your skin. This is important for the prevention of further infections. Special attention should be paid to the armpits and groin areas as the bacteria will often ‘hide’ in warm areas of the skin. This is important general infection prevention.

Decolonization of MRSA in your nose

Special nasal creams can decolonise your nose, where staph bacteria tends to hide.  this treatment tends to be reserved for those about to have surgery of some sort to help reduce the risk of wound infection. Most doctors will not give you the nasal cream for an everyday MRSA infection because overuse would make it drug resistant – it could then not be used on people before surgery to combat post operative infections. They also worry that you might catch it again from a variety of sources  within weeks.

Simple MRSA treatment – incision and drainage

Many MRSA skin infections can be treated by a wide variety of drugs and sometimes may only need incision and drainage. It will help if your MRSA test reveals exactly what type of MRSA you have. Some drugs will be inefective against the strain you may have.

Different strains need different drugs

Different strains need different drugs. Bactrim is often used for those who have the community strains. There also newer drugs created with skin infections in mind. Doctors will want to use drugs sparingly as overuse will speed up the resistance cycle. Drugs like Linezolid or Vancomycin dampen down or kill you bloodstream infection if you caught it in hospital.

Our MRSA Drug Directory

 Different conditions need different treatment

MRSA can complicate many other conditions such as pneumonia, eye infections and heart conditions. You will need to be aware of different treatment regimes for different conditions.


  1. […] There are 4 different types of treatment – these range from incision and drainage of a wound to specific drug treatment for the strain of MRSA you may have. Read More […]

  2. […] There are 4 different types of treatment – these range from incision and drainage of a wound to specific drug treatment for the strain of MRSA you may have. Read More […]

  3. […] There are 4 different types of treatment – these range from incision and drainage of a wound to specific drug treatment for the strain of MRSA you may have. Read More […]

  4. Lindsey.burger Lindsey.burger

    I need help. I have been battling MRSA infections for almost a year. It started as a small red pimple in my arm pit. Within a week I had 5-8 quarter sized pus filled sores. I had them surgically removed. Which took 3 months to heal and then moved to my other armpit. A few weeks later they began in my groin area. During that time my father developed the same sores in his armpit looking just like mine. A few weeks later my husband developed a sore in his nose. All of our wounds were treated with antibiotics with very slow results. Now my 9 year old daughter was diagnosed with one on her leg. Help what is happening. We need to know how to stop this cycle

    • Dave Roberts Dave Roberts

      Sounds like a reinfection source from a silent carrier which could be a family member or even a pet. There may also be potential infection via the workplace or regular social situation particularly if it involves children The hospital should be able to establish if they are all from the same strain within the family – it is also worth getting everyone tested


  5. Alex Alex

    In the past year, I’ve had MRSA lesions in the groin and lower abdominal area. The first time, the lesions were drained and I was treated with Clindamycin. I was clear for almost one year and had a recurrence. Septra, Rifampin, and Bactram Ointment were prescribed, no drainage was done. One week after the end of treatment, I got 2 new lesions, was put on Doxycline (100mg/2x daily), and Bactram Ointment. I saw an Infectious Disease doctor after another lesion popped up while I was being treated. I was given Rifampin for 5 days in addition to the Doxy. Two weeks later, still on Doxy and Bactram Ointment and another lesion has popped up. Have to call the ID doc on Monday.

    HELP!!!! I’m at my wit’s end. I feel like Typhoid Sally. I mist my entire body with a bleach solution 3x a week as instructed by the ID doc. I will take any and all suggestions.

    • admin admin

      The key for you is to understand what is causing the reinfection. There can be a variety of causes from nasal colonization to a source who does not become ill such as a family member, friend or family pet.

      You might want to dialogue with your ID specialist about dealing with the reinfection root


      • Alex Alex

        MRSA screens for myself and all family members are negative. I can’t afford to have the dog tested, but as a precaution, I have been using the same concentration bleach solution as I use on myself for the dog. I clean his snout, nose, feet, ears and rectal area every other day. He gets a bath once a week and gets doused with the bleach solution during the bath.
        I developed 2 more lesions while on Doxicyclin (100mg 2x daily). I was taken off Doxi and put on Trimethoprim Sulfa (one daily). One lesion still remains after 10 days, although it is smaller. ID doc says to continue what I’m doing. Meantime, I have been instructed not to go to the gym, jog, or get overly sweaty. This is not condusive with a happy, healthy lifestyle.

        • admin admin

          Have they tested and noted a specific strain of MRSA from your lesions. Different strains have different treatment profiles.Have they also tested your groin and under arm areas as they can also be hiding places for MRSA?


          • Alex Alex

            MIC’S from sensitivities of the MRSA isolated from 3 cultures were identical, but it was never DNA fingerprinted. Other than the lesions that keep popping up, groin and perianal area negative, axilla is negative. I should be sterile with the bleach baths they have me doing. I have to speak with my ID doc. I noticed that when a new lesion pops up after being clean for any length of time, it’s uaually in the same 2 places. Is it possible that the abscesses are calcified/encapsulated in some way so that the organism is harbored there? Non of the lesions ooze or form heads. They look as if someone put a hard marble under my skin.

          • admin admin

            Moving outside our area of knowledge if we comment further… hope it gets resolved


  6. Cindy Cindy

    My 2 month old grandson has Mrsa for the 2nd time now. The first time Nationwide Children’s Hospital kept him for one night and treated it with only bactrine ointment. Now his mother took him to local hometown hospital and the Drs. drew all the abcess from the boil and put him on antibiotics and cream again. The little guy has never had a fever the whole time. He got these blisters while still in the hospital just after being born. So did he get it from delivery ? Mom says she is a Mrsa carrier. Please advise. Thank You

    • Dave Roberts Dave Roberts

      Infection from the mother is not uncommon with MRSA or the closely related and more common SA. It is often does not cause an outbreak on the child and they shed it within days or weeks.

      He should now clear


  7. […] How is MRSA Treated Will I die because of MRSA? A simple MRSA treatment guide […]

  8. Nelson Nelson

    I have skin infection (boil) on my face for years, and I have tried several means of medications but still yet I see no change, But I Have gone for test.
    The result was that I have heavy growth of staph running in my blood. Please I need a remedy to this.
    thank You.

    • Dave Roberts Dave Roberts

      You should talk to your medical people about medication if this is a bloodstream infection. Skin infections respond to medication and skin hygiene methods


  9. zita myhill zita myhill

    If I have Mrsa am I still able to work as a nurse

    • admin admin

      In some countries no – they would place you on sick leave and attempt to get rid of it from your skin and nose. In many countries there is no testing among nurses for mrsa carriage. Good hygiene on the ward – hand washing particularly – should stop it reaching a patient if you have it. Doctors have it more than nurses.


  10. Caley Caley

    My 2 yr old son possibly has MRSA. He also has severe chronic neutropenia. Im worried because his count is low and he’s been on omnicef for antibiotic and nothing has changed its only getting worse. Its all over his diaper area and has 1 huge boil looking thing and then what look like blisters. Do you have any advice on possible treatment or what I should do with him next because I would assume this could potentially be dangerous and deadly for him.

  11. Justin Null Justin Null

    I have MRSA and the doctor just hit the large bump I have. She poked through the top and only a little liquid came out. She said that antibiotics will take care of the majority of the pus. I do not know if this is true and would like an explanation on why she did not drain it fully and if antibiotics could get rid of the majority of the pus. Please Help!

    • admin admin

      Incision and drainage usually involves getting as much pus as possible with the antibiotics killing the residue. It does sound a little unusual. But the key is whether it is healing or getting worse. Go straight back if it seems to be getting worse.


  12. Tasha Tasha

    I have been fighting this mrsa since aug. I’m getting them all over my body. I’m been on different medication. Now my doctor has put me on new medication I have sore on my legs and buttock the are hard the never fully drain and they come back in different places but the same are the pain is so bad. I put heat on them I get a little comfort. What should I do?

    • admin admin

      Ask if you can be referred to an infectious disease specialist. Which medication have you been on?


  13. anonymous anonymous

    i have a co-worker with mrsa- how long after she has started treatment should she wait to come back to work. we work in a hands-on environment working on peoples skin. after reading this i feel she shouldnt be working on the public????

    • admin admin

      She will need full decolonisation via the nose. It would also be helpful if she had a 5 day course of Hibiclens baths. Any skin infection she has should be covered.

      High touch occupations carry a greater responsibility

      Dave Roberts

  14. i have this, infection, and i was womdering whenit normally heals up. the infection is around old cuts and scrapes, that have healed by now. how long will i have this THING on my skin? ps, it is a very mild case

    • admin admin

      If it is MRSA it can clear after several days. If it persists you should seek medical advice.

      Dave Roberts

  15. Sharon Sharon

    My question is – Is the person infected only contagious if they have a sore with the infection in it? Once the sore is healed, do we need to keep enforcing the strict hand washing/disinfecting routine? The person infected is an 18 month old and the “hot spot” is on her bottom. It is seaping and I am currently changing diapers with rubber gloves. When that heals do I still need to change diapers with rubber gloves? Also, what do I need to look for as symptoms to make sure I don’t catch it? How do I disinfect toys/stuffed animals?

    • admin admin

      They could still be a silent carrier. But getting rid of it from their nose may offer only temporary respite as reinfection can occure again via another silent carrier, family pet etc. A hand washing pattern that includes meal times, first thing in the morning, last thing at night and after return from outside activities will reduce the risk to all by quite a lot.

      Hope this helps

      MRSA Infection

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